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Neil Risch is an American human geneticist and professor at the University of California, San Francisco (UCSF). Risch is the Lamond Family Foundation Distinguished Professor in Human Genetics and Director of the Institute for Human Genetics and Professor of Epidemiology and Biostatistics at UCSF. Known for his work on numerous genetic diseases including torsion dystonia, Risch emphasizes the links between population genetics and clinical application, believing that understanding human population history and disease susceptibility go hand in hand.〔(Risch et al. 2002 )〕 == Population genetics == Risch has conducted significant work on the nature of human differences on a geographical scale. For instance, he used social and genetic data to analyse genetic admixture from White, African, and Native American ancestry in Puerto-Rico, as well as relating this to geographical variation in Social status 〔M. Via, C. R. Gignoux, L. A. Roth, L. Fejerman, J. Galanter, S. Choudhry, G. Toro-Labrador, J. Viera-Vera, T. K. Oleksyk, K. Beckman, E. Ziv, N. Risch, E. G. Burchard and J. C. Martinez-Cruzado. (2011). History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. ''PLoS One'', 6, (e16513 )〕 Risch considers that genetic drift is a more compelling explanation for the carrier frequency of lysosomal storage diseases in Ashkenazi Jews than heterozygote advantage, in light of analysis of the results of recent genetic testing by his collaborators and himself. After mapping torsion dystonia by linkage disequilibrium (LD) analysis he found it was genetically dominant and was a founder mutation. Other work has focused on the genetic basis of Parkinson's disease, hemochromatosis, multiple sclerosis, diabetes, autism, epilepsy and hypertension. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Neil Risch」の詳細全文を読む スポンサード リンク
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